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STAFF SCIENTIST 1 - Human Regulatory Genomics Position Information: The National Library of Medicine (NLM) is one of 27 Institutes and Centers at the National Institutes of Health. NLM is a global
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the Department of Health and Human Services (HHS), its operating divisions, as well as other federal agencies. OSP also lends its expertise to assist in the development of the NIH’s legislative, budget, and
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The Tran lab in the Department of Molecular and Human Genetics is seeking a talented and motivated Postdoctoral Associate to lead projects that will examine the molecular mechanisms
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using human and rat stem cells and genetically manipulated rat models (see: PNAS 118:e2016517118, 2021; PNAS 118:e2111267118, 2021; PNAS 119:e2210633119, 2022; PNAS 120:e2213622120, 2023; Nature Commun 14
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mitochondrial mechanisms that prevent response to immunotherapy or chemotherapy directly in human tumor samples as well as mice and cell culture. The project will require in vivo assessment in mouse models
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discovery and development a “first in class” RalGTPase inhibitor as a new therapeutic in several human cancer types (Nature. 2014 20;515(7527):443-7). Using functional genomics/synthetic lethal screens
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of mouse ES cells, study of human brain cancer xenografts, and use of human iPS cells. Conducts studies of gene function during normal mammalian brain development, and how abnormalities in normal brain
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in Biomedical Engineering, Bioengineering, Microbiology, Urogynecology, Obstetrics and Gynecology or related fields. Desired expertise in human cell cultures, organoids, Organ Chips, or other in vitro
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, 2013; Nucleic Acids Research, 2012 ). The laboratory’s long-term goals are to translate our mechanistic yeast studies into human cell models to define the role these pathways play in tumorigenesis
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related to fungal pathogenesis and antifungal drug resistance in human pathogenic Aspergillus species. The successful candidate will also be expected to take on administrative responsibilities related